≥99% PurityGrowth Hormone Secretagogues
CJC-1295 With DAC
Growth-hormone pathway peptide studied for sustained signaling profiles.
Strength
Package
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Discount code
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About this compound
Molecular Specifications
CJC-1295 with DAC incorporates Drug Affinity Complex (DAC) technology — a maleimidoproprionic acid-based linker that forms a covalent Michael addition bond with free lysine residues on serum albumin following administration. This albumin binding dramatically extends the effective plasma half-life to approximately 7–10 days, converting a pulsatile GH secretagogue into a sustained, steady-state GH elevation model.
The pharmacokinetic distinction between CJC-1295 with and without DAC is fundamental — not merely quantitative. The No DAC form produces discrete GH pulses separated by troughs. The DAC form produces sustained GH elevation without troughs. These represent mechanistically different experimental conditions for studying GH axis biology.
DAC Chemistry
The DAC maleimide group reacts selectively with the free thiol of Cys34 on albumin under physiological conditions, forming a stable thioether bond. Albumin's ~19-day half-life governs the effective half-life of the CJC-DAC-albumin complex.
Research Applications
- Sustained GH elevation model research (contrast with pulsatile models)
- GHRH-R continuous vs. pulsatile activation comparison studies
- Long-duration GH axis studies in animal models
- IGF-1 plateau kinetics research vs. pulsatile IGF-1 patterns
- DAC chemistry and prodrug albumin-binding technology research
Storage & Handling
Store lyophilized powder at −20°C for long-term stability; short-term 2–8°C is acceptable. Reconstitute with bacteriostatic water; keep refrigerated at 2–8°C after reconstitution and use within typical research timelines.
For laboratory and research use only. Not for human or veterinary use, diagnostic, or therapeutic applications. Statements have not been evaluated by the FDA.
Research Disclaimer: The information below is provided for laboratory and research-use-only educational purposes. It is not medical advice. CJC-1295 With DAC is not intended for human or veterinary use, diagnosis, or therapy, and statements have not been evaluated by the FDA.
Compound Overview
What is CJC-1295 With DAC?
Research Applications
CJC-1295 With DAC in research models
Mechanism of Action
Receptor & pathway interactions studied
Purity & Testing
HPLC + mass-spec verification
Storage & Reconstitution
Handling lyophilized peptides
Researchers typically reconstitute with bacteriostatic water. Browse research supplies →
Frequently Asked
CJC-1295 With DAC research FAQ
What purity is CJC-1295 With DAC tested to?+
Every batch of CJC-1295 With DAC is tested by HPLC for purity (≥99% by area) and confirmed by mass spectrometry. The lot-specific Certificate of Analysis is available on this product page.
Is CJC-1295 With DAC intended for human use?+
No. CJC-1295 With DAC is supplied strictly for laboratory and research-use-only investigation. It is not intended for human or veterinary use, diagnosis, or therapy.
How should CJC-1295 With DAC be stored?+
Store the lyophilized powder at −20°C for long-term stability. After reconstitution with bacteriostatic water, store at 2–8°C and use within typical research timelines.
Do you ship within the United States?+
Yes. TX Research Peptides ships CJC-1295 With DAC domestically within the US with flat-rate shipping. Orders ship from the US for fast delivery to research labs.
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