≥99% PurityCognitive & Longevity
Semax
Synthetic heptapeptide investigated in cognitive and neurochemical research.
Strength
Package
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Discount code
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About this compound
Molecular Specifications
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences as a stabilized analog of the ACTH4–7 proline-rich fragment. The core MEFP sequence is derived from residues 4–7 of adrenocorticotropic hormone (ACTH), while the C-terminal Pro-Gly-Pro extension confers enzymatic stability. Semax is registered in Russia as a pharmaceutical for stroke treatment and memory improvement, providing an unusual degree of clinical data for a research peptide.
BDNF and Neurotrophin Research
The primary and most replicated mechanistic finding in Semax research is upregulation of BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor) expression in brain tissue. Published studies in rodent models have documented increased BDNF and NGF mRNA and protein levels in hippocampal and cortical tissue — findings relevant to neuroplasticity, learning, memory, and neuroprotection pathway research.
Neurotransmitter System Research
Published rodent studies have investigated Semax's effects on dopaminergic and serotonergic systems, including modulation of dopamine and serotonin turnover in striatal and frontal cortex regions — mechanisms relevant to mood, motivation, and cognitive pathway research.
Research Applications
- BDNF and NGF upregulation studies in neural tissue cultures
- Neuroprotection pathway research in ischemia models
- Dopaminergic and serotonergic neurotransmitter system modulation
- Learning and memory pathway research in rodent behavioral models
- ACTH fragment receptor pharmacology studies
Storage & Handling
Store lyophilized powder at −20°C for long-term stability; short-term 2–8°C is acceptable. Reconstitute with bacteriostatic water; keep refrigerated at 2–8°C after reconstitution and use within typical research timelines.
For laboratory and research use only. Not for human or veterinary use, diagnostic, or therapeutic applications. Statements have not been evaluated by the FDA.
Research Disclaimer: The information below is provided for laboratory and research-use-only educational purposes. It is not medical advice. Semax is not intended for human or veterinary use, diagnosis, or therapy, and statements have not been evaluated by the FDA.
Compound Overview
What is Semax?
Research Applications
Semax in research models
Mechanism of Action
Receptor & pathway interactions studied
Purity & Testing
HPLC + mass-spec verification
Storage & Reconstitution
Handling lyophilized peptides
Researchers typically reconstitute with bacteriostatic water. Browse research supplies →
Frequently Asked
Semax research FAQ
What purity is Semax tested to?+
Every batch of Semax is tested by HPLC for purity (≥99% by area) and confirmed by mass spectrometry. The lot-specific Certificate of Analysis is available on this product page.
Is Semax intended for human use?+
No. Semax is supplied strictly for laboratory and research-use-only investigation. It is not intended for human or veterinary use, diagnosis, or therapy.
How should Semax be stored?+
Store the lyophilized powder at −20°C for long-term stability. After reconstitution with bacteriostatic water, store at 2–8°C and use within typical research timelines.
Do you ship within the United States?+
Yes. TX Research Peptides ships Semax domestically within the US with flat-rate shipping. Orders ship from the US for fast delivery to research labs.
Customer Reviews
What researchers say about Semax
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