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TX Research Peptides
PE-22-28 research peptide vial≥99% Purity

Cognitive & Longevity

PE-22-28

≥99% PurityChecking Stock

Synthetic spadin analog studied for TREK-1 potassium channel interaction.

$35

Strength

💰 Mix & match bundle pricing

5+ vials 15% off · 10+ vials 25% off

Any mix of products counts — the discount applies to your whole cart at checkout. (Supplies like bacteriostatic water don't count.)

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Flat rate $12 US shipping
≥99% purity guaranteed
HPLC + MS verified
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About this compound

PE-22-28 is a synthetic peptide analog of spadin, studied in neuroscience research for its interaction with TREK-1 potassium channels. Supplied as a lyophilized powder for laboratory research applications. Independently tested for identity and purity by HPLC and mass spectrometry.

Storage & Handling

Store lyophilized powder at −20°C for long-term stability; short-term 2–8°C is acceptable. Reconstitute with bacteriostatic water; keep refrigerated at 2–8°C after reconstitution and use within typical research timelines.

For laboratory and research use only. Not for human or veterinary use, diagnostic, or therapeutic applications. Statements have not been evaluated by the FDA.

Research Disclaimer: The information below is provided for laboratory and research-use-only educational purposes. It is not medical advice. PE-22-28 is not intended for human or veterinary use, diagnosis, or therapy, and statements have not been evaluated by the FDA.

Compound Overview

What is PE-22-28?

PE-22-28 is a research peptide supplied by TX Research Peptides for laboratory investigation. It is provided as a lyophilized powder, manufactured to a minimum purity of 99% as confirmed by reverse-phase HPLC and electrospray-ionization mass spectrometry. PE-22-28 is studied in vitro and in animal models in the cognitive & longevity research category.

Research Applications

PE-22-28 in research models

Independent investigators have studied PE-22-28 in cell-culture and rodent models to characterize its biochemical activity. All references to research applications describe published in-vitro or animal studies — PE-22-28 is not approved for human or veterinary use and TX Research Peptides makes no health, therapeutic, or efficacy claims. See the Citations section for primary literature where available.

Mechanism of Action

Receptor & pathway interactions studied

Published research describes PE-22-28 interacting with receptor systems and signaling pathways relevant to its compound class. Specific receptor binding, downstream second-messenger activity, and dose-response profiles are documented in peer-reviewed laboratory studies; researchers should consult primary literature when designing experiments.

Purity & Testing

HPLC + mass-spec verification

Every batch of PE-22-28 is analyzed by reverse-phase HPLC for purity (≥99% by area) and by electrospray-ionization mass spectrometry for molecular-weight identity confirmation. Lot-specific Certificates of Analysis are provided for the strength you order and are linked above as well as on the product page gallery.

Storage & Reconstitution

Handling lyophilized peptides

Store the lyophilized PE-22-28 powder at −20°C for long-term stability; short-term storage at 2–8°C is acceptable. Reconstitute with bacteriostatic water immediately prior to use; once reconstituted, keep refrigerated at 2–8°C and use within typical research timelines. This guidance is concentration / reconstitution information only and is not human dosing advice.

Researchers typically reconstitute with bacteriostatic water. Browse research supplies →

Frequently Asked

PE-22-28 research FAQ

What purity is PE-22-28 tested to?+

Every batch of PE-22-28 is tested by HPLC for purity (≥99% by area) and confirmed by mass spectrometry. The lot-specific Certificate of Analysis is available on this product page.

Is PE-22-28 intended for human use?+

No. PE-22-28 is supplied strictly for laboratory and research-use-only investigation. It is not intended for human or veterinary use, diagnosis, or therapy.

How should PE-22-28 be stored?+

Store the lyophilized powder at −20°C for long-term stability. After reconstitution with bacteriostatic water, store at 2–8°C and use within typical research timelines.

Do you ship within the United States?+

Yes. TX Research Peptides ships PE-22-28 domestically within the US with flat-rate shipping. Orders ship from the US for fast delivery to research labs.

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