≥99% PurityCognitive & Longevity
Epitalon
Tetrapeptide explored in telomere and longevity studies.
Strength
Package
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Discount code
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About this compound
Molecular Specifications
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide developed by Dr. Vladimir Khavinson and the St. Petersburg Institute of Bioregulation and Gerontology as a synthetic analog of epithalamin — a polypeptide extract from the bovine pineal gland. Epitalon has been studied in longevity biology and aging research for over 30 years, with the primary published research focusing on telomerase activation, telomere dynamics, and pineal gland biology.
Telomere Biology and Telomerase Research
Telomeres are repetitive hexanucleotide sequences (TTAGGG) protecting chromosome ends from degradation. Telomere length shortens with each somatic cell division, and telomere attrition is recognized as a hallmark of cellular aging. Telomerase (TERT + TERC) elongates telomeres but is active primarily in germ cells and stem cells — largely silenced in differentiated somatic cells.
The seminal Khavinson et al. 2003 study demonstrated that epitalon exposure increased telomerase activity in human fetal fibroblast cell cultures and extended the cells' proliferative capacity — the anchor finding of epitalon's longevity research interest.
↗ Khavinson VK et al. (2003). Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. PubMed: 12937682
Research Applications
- Telomerase activation studies in cell culture models
- Telomere length dynamics research
- Pineal gland biology and melatonin pathway investigation
- Circadian rhythm research in aging animal models
- Lifespan and aging biology studies in invertebrate and rodent models
- Antioxidant pathway research in in-vitro models
Storage & Handling
Store lyophilized powder at −20°C for long-term stability; short-term 2–8°C is acceptable. Reconstitute with bacteriostatic water; keep refrigerated at 2–8°C after reconstitution and use within typical research timelines.
For laboratory and research use only. Not for human or veterinary use, diagnostic, or therapeutic applications. Statements have not been evaluated by the FDA.
Research Disclaimer: The information below is provided for laboratory and research-use-only educational purposes. It is not medical advice. Epitalon is not intended for human or veterinary use, diagnosis, or therapy, and statements have not been evaluated by the FDA.
Compound Overview
What is Epitalon?
Research Applications
Epitalon in research models
Mechanism of Action
Receptor & pathway interactions studied
Purity & Testing
HPLC + mass-spec verification
Storage & Reconstitution
Handling lyophilized peptides
Researchers typically reconstitute with bacteriostatic water. Browse research supplies →
Frequently Asked
Epitalon research FAQ
What purity is Epitalon tested to?+
Every batch of Epitalon is tested by HPLC for purity (≥99% by area) and confirmed by mass spectrometry. The lot-specific Certificate of Analysis is available on this product page.
Is Epitalon intended for human use?+
No. Epitalon is supplied strictly for laboratory and research-use-only investigation. It is not intended for human or veterinary use, diagnosis, or therapy.
How should Epitalon be stored?+
Store the lyophilized powder at −20°C for long-term stability. After reconstitution with bacteriostatic water, store at 2–8°C and use within typical research timelines.
Do you ship within the United States?+
Yes. TX Research Peptides ships Epitalon domestically within the US with flat-rate shipping. Orders ship from the US for fast delivery to research labs.
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